Be after/out for somebody’s blood
Definition 1 of 1
Pro Tip 1/3Anger Intensity
Implies extreme anger, not mild irritation. It suggests someone wants serious consequences. 
After the scandal, the board was out for the CEO's blood.
Pro Tip 2/3Not Literal
It's not about actual blood; it's a metaphor for seeking punishment or justice. 
The fans were after the referee's blood after the unfair game.
Pro Tip 3/3Colloquial Usage
Common in informal speech among friends or in movies, not in formal or professional settings. 
When Joe crashed the car, his dad was after his blood.