Be drugged up to the eyeballs
Definition 1 of 2
Pro Tip 1/3Slang Usage
The phrase is often used informally to imply excessiveness. 
At the party, everyone was drugged up to the eyeballs.
Pro Tip 2/3Negative Connotation
There’s usually a negative judgment or concern implied. 
He can't make proper decisions when he's drugged up to the eyeballs.
Pro Tip 3/3Figurative Speech
It's an exaggeration and doesn't mean drugs are literally up to someone's eyeballs. 
She looked drugged up to the eyeballs, stumbling around.