Cholesterol/kəˈlestərɔːl/ Definition 1 of 2Pro Tip 1/3Body Importance Cholesterol is not all bad; it's vital for building cells. Your body needs some cholesterol to function properly. Pro Tip 2/3Health Context Cholesterol is often discussed in health and diet topics. Conversations about a healthy lifestyle include cholesterol talk. Pro Tip 3/3Monitoring Levels Cholesterol levels can fluctuate; regular checks are essential. She has her cholesterol tested annually to monitor her health.