Copperhead/ˈkɑːpərhed/ Definition 1 of 3Pro Tip 1/2Cautionary contexts Copperhead often appears in contexts warning about the dangers of these snakes in the wild. He saw a sign: 'Watch out for copperheads!' Pro Tip 2/2American snake Copperhead specifically refers to an American venomous snake, not found worldwide. Copperheads are native to the eastern US.