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Drudgery
Negative Tone
Use 'drudgery' to express a strong negative feeling about a task or job that is tiring and repetitive. 
Not Physical Only
'Drudgery' isn't limited to physical tasks; it can apply to mentally exhausting activities too. 
Emotional Impact
The word 'drudgery' can imply that the work has a dulling effect on one's spirits or enthusiasm. 