Go/set about your work
Definition 1 of 2
Pro Tip 1/3Initiating Action
Often implies the start of a focused or structured task. 
With the strategy meeting due, she set about her work drafting the report.
Pro Tip 2/3Continued Effort
Can imply resuming work rather than beginning from scratch. 
After lunch, he set about his work with renewed energy.
Pro Tip 3/3Self-driven
Implies taking initiative without needing prompting. 
Once the instructions were clear, the team set about their work.