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Harridan
Negative Connotation
Harridan has a strongly negative tone, often showing the speaker's disapproval of the woman's behavior. 
Gender Specific
The term 'harridan' is used exclusively for women, implying a stereotype that should be used cautiously. 
Avoid Misuse
Be careful not to misuse 'harridan' to describe any woman who is simply assertive or strong-willed. 