Bill Walton

My life changed irrevocably four-and-a-half years ago when my spine failed and collapsed. I spent two years on the floor, in excruciating, debilitating and unrelenting pain. I can only describe the pain as being submerged into a vat of scalding acid that has an electric current running through it. And you can never get out, ever.

American Athlete

Adoniram Judson

The future is in our power. Let us, then, each morning, resolve to send the day into eternity in such a garb as we shall wish it to wear forever. And at night, let us reflect that one more day is irrevocably gone, indelibly marked.

American Clergyman

Donald Johanson

This was the most important discovery I had ever made in my life. It was a discovery which has irrevocably changed my whole life's direction. It immediately elevated me to the status of one of the world's leading anthropologists.

American Scientist

Mohsin Hamid

Stories helped me unite parts of my existence that might otherwise have seemed irrevocably split by geography and time. And stories helped me find a future in which I, such a mongrel, could be comfortable.

Pakistani Writer

Lynn Coady

The creative process taps into our deepest subconscious, and we are each of us sex-crazed - products of a shame-based Judeo-Christian culture that has irrevocably warped us all to varying degrees.

Canadian Novelist

Henry Rollins

If I were a doctor, I would prescribe that you addict yourself deeply and irrevocably to music and never, ever seek cure outside of more music. It really is the best drug available.

American Musician

Pamela Druckerman

Even for natives, French satire is rarely laugh-out-loud funny. Its unspoken punch line is typically that things have gone irrevocably wrong, and the government is to blame.

American Writer

Arthur Henderson

On the contrary, the characteristic element of the present situation is that economic questions have finally and irrevocably invaded the domain of public life and politics.

British Politician

Peter Ustinov

I was irrevocably betrothed to laughter, the sound of which has always seemed to me the most civilised music in the world.

English Actor

Horace

A word, once sent abroad, flies irrevocably.

Roman Poet

Use 'irrevocably' when you want to stress that something has been changed so completely that there's no going back.

Finality Emphasized

'Irrevocably' adds a serious tone and often carries emotional weight, suggesting deep impact.

Emotional Weight

Can describe figurative change, not just physical; relationships and situations can be 'irrevocably' affected.

Not Literal Only

 nation states is irrevocably flawed so let me not pretend that utopia is imminent but for the first time ever there is a crescendo of hope there is a real possibility that under michelle bachelet united nations will finally and seriously address the myriad of women's

Advocating for gender...

 it made the air impossible to breathe, burned their eyes, and caused huge blisters on exposed skin. Scientists tried desperately to develop an antidote to this vicious weapon of war. In the process they discovered the gas was irrevocably damaging the bone marrow

How does chemotherapy...

 which is something that you loved doing as a congresswoman, and Mark, you were happily preparing for your next space shuttle. And suddenly, everything that you had planned or expected in your lives was irrevocably changed forever. Mark Yeah, it's amazing,

Gabby Giffords and Mark...

 Geographic until then so in the end maybe I didn't change the world but that world changed me profoundly and irrevocably I don't I don't look at prostitution as a victimless crime