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Ladyship
Polite Address
Use 'ladyship' respectfully when speaking to or about noblewomen, or sarcastically to mock someone acting superior. 
Historical Use
'Ladyship' was more common in the past and might appear frequently in historical or period pieces. 
Cultural Nuance
Being aware of cultural norms is crucial, as incorrectly addressing someone as 'ladyship' might be seen as mockery. 