Neutralize/ˈnuːtrəlaɪz/ Definition 1 of 4Pro Tip 1/2Broad Applications Use 'neutralize' to describe making various harmful things harmless, not just physical objects. A well-crafted apology can neutralize resentment. Pro Tip 2/2Metaphorical Use 'Neutralize' can be used metaphorically to talk about reducing an effect or influence. The company's new policy neutralized consumer complaints.