Splenetic
/spləˈnetɪk/
Definition 1 of 2
Pro Tip 1/3Anger Expression
Use 'splenetic' to describe someone showing sharp irritation due to annoyance or anger. 
After the long delay, her splenetic comments were understandable.
Pro Tip 2/3Negative Mood
'Splenetic' suggests a persistent negative mood rather than a temporary state. 
The splenetic mood in the office made everyone uncomfortable.
Pro Tip 3/3Literary Flair
'Splenetic' is often used in literary contexts for dramatic effect. 
In the novel, the splenetic old man constantly grumbled about change.