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Strike at

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Physical ConfrontationPlay
Used when describing a physical attack or motion towards someone or something. SlideHe struck at the intruder with a fierce blow.
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Effort to SolvePlay
Implies an attempt to tackle a challenge or problem, not necessarily physical. SlideThe committee struck at the issue with several meetings.
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Metaphorical UsePlay
Often used metaphorically to describe an attack on concepts, beliefs or reputations. SlideThe article struck at the politician's credibility.