Synthesize/ˈsɪnθəsaɪz/ Definition 1 of 4Pro Tip 1/2Combining Elements Think of 'synthesize' like mixing ingredients to create a new dish. Chefs synthesize flavors to create a unique taste. Pro Tip 2/2New Unity 'Synthesize' implies forming something new that didn't exist before. Artists often synthesize various styles to invent original artwork.