Uphill/ˌʌpˈhɪl/ Definition 1 of 3Pro Tip 1/2Physical Effort Using 'uphill' can imply the physical challenge or difficulty of an action. After the long hike uphill, they were exhausted. Pro Tip 2/2Literal Slope 'Uphill' is often used to describe the literal slope of terrain, not a figurative action. The car struggled as it went uphill.