Vex/veks/ Definition 1 of 4Pro Tip 1/2Mild Annoyance Use 'vex' to express a light but persistent sense of annoyance. His habit of interrupting others during conversations began to vex me. Pro Tip 2/2Collocation Understanding Pay attention to collocations like 'vex someone's spirit' which imply deep annoyance or distress. The disrespectful comments began to vex her spirit.