What’s your poison?
Definition 1 of 1
Pro Tip 1/3Informal Setting
The phrase is used casually, often among friends or in laid-back environments like bars. 
At the house party, Mark grinned and asked, 'What's your poison tonight?'
Pro Tip 2/3Drink Selection
It specifically refers to choosing a drink, usually alcoholic, but can also be non-alcoholic. 
The hostess at the gathering asked with a smile, 'What’s your poison? We have cocktails and juices.'
Pro Tip 3/3Ice Breaker
It can be used as an ice breaker in social situations to start a conversation with someone new. 
Jim approached the new colleague at the office party saying, 'Hi, I'm Jim. What's your poison?'